A fresh set of 20 random questions is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
1. The tissues most sensitive to atropine are:
A. The salivary, bronchial and sweat glands
B. The gastric parietal cells
C. Smooth muscle and autonomic effectors
D. The heart
2. Which of the following is a mixed alpha and beta agonist?
A. Dobutamine
B. Fenoldopam
C. Epinephrine
D. Phenylephrine
3. Which of the following inhalants is a gas anesthetic?
A. Halothane
B. Isoflurane
C. Nitrous oxide
D. Desflurane
4. This drug is an inhibitor of renin synthesis:
A. Propranolol
B. Enalapril
C. Diazoxide
D. Losartan
5. Which direction would a competitive antagonist (plus agonist) shift the dose-response curve when compared to a full agonist?
A. To the left
B. To the right
C. Down
D. Up
6. Enzyme drug used for acute leukemia treatment:
A. Dihydrofolate reductase
B. Asparaginase
C. Aromatase
D. DNA gyrase
7. The drug acts at the proximal tubule:
A. Loop diuretics
B. Thiazide diuretics
C. Potassium-sparing diuretics
D. Carbonic anhydrase inhibitors
8. The vast majority of drugs have molecular weights (MW) between 100 and 1,000. Large drugs, such as alteplase (t-PA), must be administered:
A. Into the compartment where they have their effect
B. Orally so they do not absorb too quickly
C. Rectally to prevent irritation to the stomach lining and vessels
D. Via the intraosseous (IO) route
9. Characteristics of cocaine abstinent syndrome include all of the following phases EXCEPT:
A. Feeling of depression, irritability, confusion, insomnia (the first 3 days)
B. Depression, apathy, excessive appetite, a wish to sleep (the subsequent 1-2 days)
C. Psychosis as color visual and auditory hallucinations (for 3 day)
D. New attack of depression, anxiety, irritability, dullness, intense thirst for cocaine (after 1-5 days improvement)
10. Which of the following is NOT an approach to drug development?
A. Chemical modification of a known molecule
B. Random screening for biologic activity (e.g. natural products)
C. Rational drug design
D. Combination of known drugs (e.g. Tylenol with codeine)
11. Which of the following opioid analgesics is a strong kappa receptor agonist and a mu receptor antagonist?
A. Naltrexone
B. Methadone
C. Nalbuphine
D. Buprenorphine
12. Mu (?) receptors are associated with:
A. Analgesia, euphoria, respiratory depression, physical dependence
B. Spinal analgesia, mydriasis, sedation, physical dependence
C. Dysphoria, hallucinations, respiratory and vasomotor stimulation
D. Analgesia, euphoria, respiratory stimulation, physical dependence
13. Glucagon can be used in the following situations, EXCEPT:
A. Severe hypoglycemia
B. Severe hyperglycemia
C. Endocrine diagnosis
D. Beta-blocker poisoning
14. In which of the following cases could a dose-response curve be constructed?
A. Prevention of convulsions
B. Prevention of arrhythmias
C. Reduction of death
D. Reduction of fever
15. All of the following drugs may cause Hirsuitism, except
A. Danazol
B. Phenytoin
C. Norethisterone
D. Flutamide
16. Characteristic unwanted reaction which isn’t related to a dose or to a pharmacodynamic property of a drug is called:
A. Idiosyncrasy
B. Hypersensitivity
C. Tolerance
D. Teratogenic action
17. Most phenothiazine derivatives have:
A. Antihistaminic activity
B. Anticholinergic activity
C. Antidopaminergic activity
D. All of these
18. What cells produce hydrochloric acid in the stomach?
A. Gastrin-producing cells
B. Parietal cells
C. Mucus-producing cells
D. None of these
19. Indicate the nootropic agent useful in disorders of brain circulation:
A. Aspirin
B. Pyracetam
C. Warfarin
D. All the above
20. Which one of the following non-narcotic agents inhibits mainly cyclooxygenase (COX) in CNS?
A. Paracetamol
B. Ketorolac
C. Acetylsalicylic acid
D. Ibuprofen
Public Hospital 554/7 New Anaj Mandi, Fatehabad 125050 M: 9810570740, 9810571993
Tel: 01667221011, 9810570740, 9810571993 facebook.com/doctorkc